Travel I 75 from Florida to Ohio

Interstate 75 North at Exit

Avoiding The Smoky Mountains - Ohio to Florida. Help!?

I've posted in the Florida forums and I've been given quite a few options for the best route. Here's my conundrum... We're leaving (my DH and three older kids, 11, 14, 15) to go to Miami on December 22nd from Cleveland, Ohio and driving back January 5th or so. To some, mountain driving is worry-free and beautiful. I usually agree! I've done the Rockies a few times and love it. My problem is it will be winter and I'm not sure yet of the forecast. I'm willing to drive a bit longer to avoid any "scary" turns/mountains. I'm a bit afraid of there being a snow storm or ice, etc.

Here are my options for driving along with some of the pros and cons I've gathered up. Is it worth bypassing them or should I just not worry at all? Please chime in if you have any advice. Also, once in FLA, a couple of these routes take me down the center of FLA rather than the coast. I hear the center is a better drive sight-wise? Also haven't picked the city to stay in going or coming as we'll be making it a 2-day drive each way. So far contemplating Charleston, Near Atlanta somewhere? Maybe "South of the border? which I hear is kind of tacky?" I'd like a cool, nice place that my kids will think is okay and maybe learn/see something, but my main concerns are the mountains. I will likely be able to bunk in any city without too much worry and while the views are desirable, I'm okay with not having them as long as we're safe. Thanks in advance for any help!

I-77 S and I-95 S - 1, 241 mi, 20 hours - Fastest, but goes through mountains and down the east coast of FLA.

I-75 S - 1, 372 mi, 22 hours - Looks like it goes a bit around the Smokies? Not sure exactly the big difference mountain-wise between this and the one above... Takes me through the center of FLA.

I-65 S - 1, 479 mi, 1 day - Long, but goes all the way around the mountains?

Then there's the option of going over the eastern border of PA and then take the PA turnpike down to I-70. To avoid all the crazy DC traffic this option was given... I-70 and Hwy 522. Continue on I-81 to I-66 to Hwy 17 toward Fredricksburg until you reach I-95 south. All roads are divided except portions of 522. (not sure exactly the time on this one.)

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